KMID : 0364820120480010037
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Korean Journal of Microbiology 2012 Volume.48 No. 1 p.37 ~ p.41
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Biotransformation of trans,trans-farnesol by Wood Rot Fungi
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Kim Young-Hun
Lee Su-Yeon Park Mi-Jin Choi In-Gyu Lee Jae-Won
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Abstract
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In this study, we screened and evaluated possibility of wood rot fungi as biocatalyst for biotransformation of
sesquiterpenes. Screening were performed to select the most promising microorganisms with ability to
biotransformation the substrate trans,trans-fanesol. Trans,trans-farnesol which is synthesized precursor of
sesquiterpenes was used for resistance test on 19 of wood rot fungi. From the 19 tested wood rot fungi, 5 were
selected by resistance test on different concentration of trans,trans-fanesol. Biotransformation was performed with
selected wood rot fungi on liquid culture. The metabolites detected by GC-MS analysis were nerolidol for
Laetiporus sulphureus var. miniatus (jungh) Imaz and eicosane for Coriolus versicolor (L.Fr) Prlar and isoborneol
for Fomitopsis pinicola and isocyclocitral for Lampteromyces japonicas. As the results, wood rot fungi could be
potential biocatalyst for biotransformation of sesquiterpenes.
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KEYWORD
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biotransformation, sesquiterpene, trans, trans-farnesol, wood rot fungi
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